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Multicentre Cohort Study in Alcoholic Hepatitis (MICAH)

MICAH is actively recruiting patients with alcohol-related hepatitis and acute decompensation of cirrhosis.

Please
contact us if you are a hospital site interested in participating.



Objective:
To identify and validate biomarkers and scoring systems which predict the outcome of alcoholic hepatitis.

Aim:
To recruit patients with Alcoholic Hepatitis (AH), irrespective of severity, to evaluate performance of the prognostic scoring systems and diagnostic and prognostic biomarkers. In order to evaluate diagnostic biomarkers, we will also recruit control patients with acute decompensation of cirrhosis (AD).

Design:
Prospective multi-centre observational cohort study with nested case-control studies for mortality, infection and acute kidney injury.
The study will collect patient data and samples for 90 days and continue remote follow up for 10 years. 
Active Recruitment Sites

Aintree University Hospital

Barnsley Hospital

 

Cambridge University Hospital

 

Derby Teaching Hospitals

East Kent Hospital

NHS Forth Valley - Forth Valley Royal Hospital

NHS Greater Glasgow and Clyde

NHS Grampian - Aberdeen Royal Infirmary

Gloucestershire Hospitals

Guy's and St Thomas' Hospital

 

Hull and East Yorkshire Hospitals

Imperial College Healthcare NHS Trust

Leeds Teaching Hospital

NHS Lothian - Royal Infirmary of Edinburgh

Oxford University Hospitals

Plymouth NHS Trust

Portsmouth Hospitals

Royal Devon and Exeter

Royal Liverpool and Broadgreen University Hospitals

Royal Free Hospital

St George's University Hospitals

Taunton and Somerset NHS Foundation Trust

The Newcastle Upon Tyne Hospitals

 
Torbay and South Devon NHS Foundation Trust
University Hospital Southampton

 
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